café scientifique


Next meeting:
Monday 10th October 2016

Growing Mini-Brains to Help Understand Cancer
By Ryan Mathew


Stem cells can be used to create small (2-4mm) 3D structures that resemble human brains in early development. This technology is enabling the study of developmental disorders of the brain, but could also provide a model for studying brain tumours. We want to make the model personalised so we’re using ground-breaking technology to reprogram brain tumour cells – from  patients undergoing surgery at Leeds – into stem cells. Combining these approaches allows us to grow mini-brains from these patient-derived reprogrammed stem cells. It is hoped that this pioneering mini-brain model will allow us to study the biology of brain tumours and act as a platform for personalised drug testing.


Ryan Mathew completed his training as a Neurosurgeon at Leeds General Infirmary. He has a specialist interest in Neuro-Oncology, in particular Low Grade Gliomas and Awake Surgery. He is currently a Cancer Research UK funded Clinical Research Fellow at the Cancer Research UK Leeds Centre where he is undertaking a PhD into brain tumour stem cells and modelling. He works in the Wurdak Group. On completion of his PhD, he hopes to be appointed as a Consultant Academic Neurosurgeon, dividing his time between clinical and lab-based research work.


Coming soon:

Monday 10th October 2016
“Growing Mini-Brains to Help Understand Cancer”
By Ryan Mathew

Monday 14th November 2016
“Neutrino Astronomy”
By Alan Watson

Monday 12th December 2016
“William Gascoigne – Leeds Astronomer at the Forefront of the Scientific Revolution”
By David Sellers

About Café Scientifique

Café Scientifique is a place where people can meet to hear eminent speakers on all things scientific. The events are extremely popular with lively discussion and informative talks. Topics are always relevant, cutting edge and up-to-date. They are often taken from a wider global discussion.

All are welcome. The Café is held at The New Headingley Club on St Michael’s Road.

For information on topics please check back here for updates or for more information see the e-newsletter or the HDT newsletter.

To be added to the Café Scientifique mailing list please contact: or fill out the online form opposite.



Monday 12th October 2015
“Health Freaks on Trial”
By Martin Bland
Health Sciences
University of York

Monday 2nd November 2015
“Mathematics of Sea Waves”
By Tomasz Salwa and Floriane Gidel
School of Mathematics
University of Leeds

Monday 14th December 2015
“Our Technological Footprint on the Universe
–  in 63 steps”
By Dave Webb

Monday 11th January 2016
“Imaging Positrons Inside the Human Body”
By Charalampos Tsoumpas

Monday 8th February 2016
“From Dark Satanic Mills to DNA: the Scientific Heritage of Leeds and how it Changed the World”
By Kersten Hall

Monday 14th March 2016
“The Worst of Times:
How Life on Earth Survived Eighty Million Years of Extinctions”
By Paul Wignall

Monday 11th April 2016
“Monster Magnets: Stellar Birth Control”
By Sven Van Loo

Monday 9th May 2016
“Ask for Evidence”
By Danae Dodge

Monday 13th June 2016
“Herding Hemingway’s Cats: how do genes work?”
By Kate Arney

Monday 11th July 2016
“Climate Change & Rocky Coasts”
By Sue Hull

Monday 12th September 2016
“The Mobility Transformation”
By John Whitelegg


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additional info

7:30pm – 9:30pm

New Headingley Club
56 St Michael’s Road
Tel: 0113 2757712 (for info. on venue)

Entry £3

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